Product Overview

Cord blood CD34+ cells are known to contain hematopoietic stem and progenitor cells, and are ideal for studies relating to transplantation and stem cells as cord blood derived cells tend to be more naïve than similar cells derived from other tissue sources.

High Purity and Viability

Lonza cord blood CD34+ cells are isolated from cord blood mononuclear cells (MNCs) via positive immunomagnetic separation and are guaranteed to have a purity of ≥90% as indicated by CD34+ expressing cells. They are guaranteed to contain  ≥1 million viable cells per ampoule. HIV-1 and hepatitis B are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Choices in Tissue Source

Cord blood CD34+ cells tend to be more naive than hematopoietic stem cells from other tissue sources. Thus, they can be a great tool when trying to bypass HLA mismatch issues. However, the number of cells available per donor is limited and can pose a challenge in your research. If you are looking for large numbers of hematopoietic stem cells from the same donor, CD34+ cells derived from bone marrow might be a good option.

Lonza guarantees the performance of Clonetics^®/Poietics^® cells only if appropriate Clonetics^®/Poietics^® media and reagents are used exclusively and the recommended storage and use protocols are followed. Any modifications made to the recommended cell systems including the use of alternative media, reagents or protocols, will void cell and media performance guarantees. If you need assistance in selecting the appropriate media, reagents, or protocol, please contact Lonza Scientific Support.

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Benefits

• Ready to use
• Large donor pool
• High purity with > 90% CD34+ cells

Applications

• Humanized mouse generation
• Autoimmune disease
• Applications requiring more naïve HSCs than those from bone marrow

Storage and Content

1 x cryopreserved ampoule containing ≥1 million cells