Lonza

NHCF-V – Human Ventricular Cardiac Fibroblasts

Catalog No : CC-2904

Cryopreserved ampule of Normal Human Ventricular Cardiac Fibroblasts (NHCF-V) containing ≥ 500,000 cells

Product Overview

 

Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and -V) isolated from the atrium or ventricle. Cells are isolated from normal, adult heart tissue. Cryopreserved cells are shipped at passage 2. 

CloneticsTM NHCF-V & -A are guaranteed through 5 population doublings and express ≥90% collagen I and ≤10% Von Willibrand factor VIII after thaw. CloneticsTM AoAF are guaranteed through 10 population doublings and are negative for alpha smooth muscle actin. All cells test negative for mycoplasma, bacteria, yeast and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis (CoA) is provided for each cell lot purchased.  

 

 

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Benefits

 

  • Assured for experimental use up to 15 population doublings 
  • Express ≥90% collagen I and ≤10% Von Willibrand factor VIII
  • All cells test negative for mycoplasma, bacteria, yeast, and fungi
  • HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots
  • Certificate of Analysis provided for every cell lot

 

Applications

 

  • Vascular diseases
  • Neointimal formation
  • Vascular remodeling
  • Atherosclerosis
  • Hypertension
  • Myocardial repair
  • Extracellular maintenance during cardiac cell / tissue growth
  • Cardiac Fibrosis Paracrine signalling
  • Toxicology
  • Gene expression

 

Storage and Content

1 x Cryopreserved ampule NHCF-V containing ≥ 500,000 cells/vial