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Rat Cerebellar Granular Neurons

Catalog No : R-CB-503

Cryopreserved ampule of Rat Cerebellar Granular Neurons containing ≥ 4 million cells
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Product Overview

 

CloneticsTM Rat Cerebellar Granular Cells are isolated from cerebellar cortex of adult Sprague Dawley rats at postnatal day 8. Cerebellar granular cells utilize glutamate as their neurotransmitter and as such, are the only excitatory neurons within the cerebellar cortex.

All other neuronal cell types employ GABA as a neurotransmitter. Granular cells arise during the latter stages of neuronal development of the cerebellar cortex and are the most abundant single neuronal type in the mammalian brain. These are highly homogeneous populations of granular cells containing less than 5% GABAergic neurons, as assessed by GABA immunoreactivity.

Recommended Media: PNGMTM-A BulletKitTM (CC-4512)

 

 

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Benefits

 

  • Ready-To-Use 
  • >95% pure granular cells, with glia
  • No tissue dissection or animal handling required 
  • Increased data reproducibility
  • Characteristic morphology and staining tests confirm tissue origin and cell type
  • Negative for mycoplasma, bacteria, yeast and fungi
  • Certificate of Analysis (CoA) is available for every batch 

 

 

Applications

 

  • Electrophysiology
  • Neurotransmitter release
  • Ion channels
  • Glutamate receptor biology
  • Neuronal apoptosis and toxicity
  • Nitric Oxide and cGMP pathway
  • Neurite outgrowth

 

 

Storage and Content

≥ 4,000,000 cryopreserved cells per ampule