CARR Biosystems

UniFuge Pilot®_ A Single-Use System for Cell Processing

Catalog No : UFMini®

Achieve high separation efficiency and up to 98% cell viability in early-stage development with the UniFuge Pilot automated centrifuge. Optimize low-shear, high-throughput processing of mammalian, bacterial, and insect cells for pilot-scale production that scales up or down easily.

Overview

The UniFuge Pilot has a lightweight single-use module (rotor and separation chamber) and integral tube set that comes pre-gamma irradiated to ensure easy installation, clean-up, and disposal. These sterile connections can be fitted to existing setups upon request.

  • Low noise level (below 80 dB) during operation
  • Continuous discharge of supernatant and intermittent discharge of cell culture
  • Reduces host cell proteins and other contaminants
  • Compatible with various processing volumes and concentration targets
  • Different jacket options are available
Minimum Working Volume
1.8 L
Flow Rate
1-4 L/min
G-force
Up to 4,000 xg

 

Benefits of CARR Biosystems UniFuge Pilot

Versatility : Increase cell recovery and efficiency across multiple applications with low-shear, high-throughput processing in the early stages of development.

Performance : Improve your product yield and purity with the UniFuge Pilot’s tubular bowl centrifugation, enabling low-shear separation of even the most fragile cell types.

Reproducibility : De-risk the scale-up and tech transfer process with intuitive software, technical automation, and reduced operational costs.

Optimization : Maximize quality and reduce waste with the UniFuge Pilot’s closed system, small residual volume, and low absorption, ensuring more product from less culture volume.

 

Rec. Processing Volume 25-500L
Max Flow Rate 1-4L/minute
Rotational Force 300 to 4,000 xg
Weight 291 kg (690 lbs)
Maximum Case Pressure 6.9 bar (100 psi)
Programmable Logic Controllers (PLC) Allen-Bradley®
Feed Center for low-shear operation
Power Configurations 120/230 Volts Alternating Current (VAC), 50/60 Hz, Single-Phase (1-Ph), 10 A
Pneumatic Clean, dry air supply 4.5-6.6 bar (65-95 PSI), 57 Standard Liters per Minute (SLPM), 2 Standard Cubic Feet per Minute (SCFM)

Single-Use Module

  • Components compliant with physiochemical tests: intermittent discharge of cell culture: USP <87> <88> Class VI, USP 661 (or ISO 10993) for plastic materials
  • Concentric tubes to introduce feed and remove supernatant
  • Compliant with ISO 11137 to Sterility Assurance Level (SAL) 10-6

 

UniFuge® Pilot Single-Use Centrifuge | CARR Biosystems