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CARR Biosystems

U2k®: A Single-Use System for Scaling Up Cell Processing

Catalog No : U2k®

Preserve cell health during high-throughput primary clarification and harvesting with the high-capacity U2k® centrifuge. Improve productivity without compromising cell viability with low-shear processing for large-scale production and commercialization.
제품문의

Overview

The U2k is a scaled-up version of the UniFuge Pilot, perfect for the later stages of development. It has a single-use module (rotor and separation chamber) and integral tube set that comes pre-gamma irradiated to ensure easy installation, clean-up, and disposal. These sterile connections can be fitted to existing setups upon request.

  • Low noise level (below 80 dB) during operation
  • Intermittent discharge of supernatant and cell culture
  • High cell density (up to 25% PCV)
  • Compatible with various processing volumes and concentration targets
  • Integrated cooling jacket

Minimum Working Volume 9 L

Typical Flow Rate 5-20 L/min

G-force Up to 3,000 xg

 

Benefits of CARR Biosystems U2k

Efficiency : Streamline cell processing with intuitive software and full automation, reducing operational costs and enhancing process intensification.

Performance : Improve your product yield and purity with the U2k’s tubular bowl centrifugation, enabling low-shear separation of even the most fragile cell types.

Versatility : Increase cell recovery and efficiency across multiple applications with low-shear, high-throughput processing in the later stages of development.

Capacity : Process hundreds of liters of product per hour with the high-capacity U2k—maximize cell recovery and product output for large-scale production.

 

Rec. Processing Volume 500 - 2,000L
Max Flow Rate 5-20 L/min
Rotational Force 500 to 3000 xg
Weight 912 kg (2010 lbs)
Maximum Case Pressure 6.9 bar (100 psi)
Programmable Logic Controllers (PLC) Allen-Bradley® or Siemens®
Feed Center for low-shear operation
Power Configurations

Three-phase voltage supply

US: 230V/60 Hz, 80A or 460V/60 Hz, 40A

Europe: 400V/50 Hz, 46A

Japan: 200V/60 Hz/50 Hz, 90A

Others as needed
Pneumatic Clean, dry air supply 6.2-8.3 bar (90-120 PSI), 100 Standard Liters per Minute (SLPM), 3.5 Standard Cubic Feet per Minute (SCFM)

 

Single-Use Module

  • Module minimum working volume 9L with 9.5mm (3/8”) inner diameter x 12.7mm (1/2”) outer diameter silicone tubing
  • Physiochemical: USP <87> <88> Class VI, USP 661 (or ISO 10993) for plastic materials
  • Concentric tubes to introduce feed and remove supernatant
  • Manufactured in ISO 13485 facility with Class 7 cleanroom

 

U2k Single-Use Centrifuge | CARR Biosystems